GDP-fucose Protein O-Fucosyltransferase 1
Enzyme, Fucose, Serine, Threonine, Epidermal growth factor, Notch signaling pathway
978-620-0-05259-9
620005259X
96
2013-01-10
29.00 €
eng
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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. GDP-fucose protein O-fucosyltransferase 1 (POFUT1) is an enzyme responsible for adding fucose sugars in O linkage to serine or threonine residues between the second and third conserved cysteines in EGF-like repeats on the Notch protein. The protein is an inverting glycosyltransferase, which means that the enzyme uses GDP-β-L-fucose as a donor substrate and transfers the fucose in O linkage to the protein producing fucose-α-O-serine/threonine.
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Biología
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